Clinico-Epidemiological study of Alopecia Areata

Objective To evaluate the clinical and demographical pattern of alopecia areata [AA] and their association with other diseases

Methods A cross-sectional multicentric study of 410 patients with AA was carried out during the period of January 2013 to December 2014. A detail clinical and demographical pattern of the disease was taken in a prescribed proforma along with the association of other diseases, if present

Results A total of 410 patients with AA were included in the study with age ranging from 1 year to 74 years, out of which 206 were males and 204 females. The commonest age at onset was 21-30 years. Multilocular patches were the commonest presentation. Based on the pat

Familial pseudoxanthoma elasticum: report of three case series in a single family

Pseudoxanthoma elasticum is a rare autosomal recessive skin disease with a slight female preponderance and often presents a therapeutic challenge due to additional risk to eyes and cardiovascular system. Clumping and distortion of elastic fibres in target organ leads to deposition of calcium and impair the function of elastic fibres of mid and deep dermis, media and intima of midsized arteries, Bruch's membrane in eye. Here we present three cases in the same family who presented with yellowish flat plaques, papules in the front and lateral side of the neck

Lupus vulgaris of centrofacial area - a peculiar presentation

Lupus vulgaris is a cutaneous manifestation of Mycobacterium tuberculosis infection. It assumes various clinical forms including plaque, ulcerative, hypertrophic, vegetative, papular and nodular type. We here present an unusual case of a ten-year-old girl diagnosed as hypertrophic lupus vulgaris of centrofacial area including nose. Histopathological examination and bacteriological studies were carried out to establish the diagnosis. Unlike plaque type, hypertrophic variety is quite uncommon and only few cases have been reported. Its peculiar appearance on the face which is hardly described in previous literatures and well response to antitubercular therapy prompted us to report it

Onychomycosis in Eastern India - study in a peripheral tertiary care centre

To find out various clinical patterns, etiologic agents and to evaluate the clinicomycologic correlation. Two hundred and forty nine cases of clinically suspected onychomycosis were included in this study. Clinical patterns were noted and sample collected from most severely affected nail. They were subjected to direct microscopy and culture. Distal and lateral subungual onychomycosis was the commonest clinical pattern [56.6%] followed by proximal subungual onychomycosis [15.7%], total dystrophic onychomycosis [12.1%], white superficial onychomycosis [10.8%] and chronic paronychia [4.8%]. 126 cases [50.6%] were confirmed by either microscopy or culture whereas 123 cases [49.4%] were negative by both. Dermatophytes were most common [55.9%] cause of onychomycosis. Amongst them Trichophyton rubrum was the most common isolate [65.9%]. Candida albicans was important [79.2%] amongst the yeast isolates. Nondermatophytic moulds were involved in 15.5% of cases. Onychomycosis might be an important cause of absenteeism amongst the working classes in this part of India. Yeasts and nondermatophytic moulds are gradually becoming an important cause of onychomycosis in different areas of the world. So, early diagnosis and initiation of antifungal treatment should be the approach to safeguard the social, emotional and physical well being of the patients

Eccrine syringofibroadenoma: an unusual presentation of a rare disease

Eccrine syringofibroadenoma [ESFA] is a rare disorder with differentiation towards ductal eccrine apparatus. There are a variety of clinical manifestations and distribution of lesions but the histopathological features are remarkably similar with benign appearing anastomosing cords of eccrine ductal epithelial cells with or without lumina formation, are embedded in loose fibrovascular stroma. We report a case of 55-year-old Muslim man having large pale pink slightly verrucous plaque on right upper back since last 20 years with central ulceration for 8 years. Punch biopsy was done and showed features of ESFA